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  • FSA & HSA eligible
  • Prescribed by licensed MDs
  • All 50 states
Antha

Why do I keep getting UTIs?

Three quick questions. No sign-up.

Question 1 of 3

How many UTIs have you had in the past year?

Two women walking arm in arm down a city street, laughing

Less estrogen, less protection

For perimenopausal and menopausal women, the cause is often low estrogen. Estrogen keeps the lining of your vagina and urethra thick, with plenty of good bacteria. When it drops, the lining thins and E. coli moves in.

With estrogen
Cross-section of a thick, layered lining with many good bacteria on its surface.
  • Plenty of good bacteria
  • Stored sugar feeds them
  • A thick lining
  • Good blood flow
After estrogen drops
Cross-section of a thin lining with few good bacteria and E. coli attached to its surface.
  • Few good bacteria
  • E. coli settles in
  • A thin lining
  • Less blood flow

What urologists recommend

“In perimenopausal and postmenopausal women with [recurrent UTIs], clinicians should recommend vaginal estrogen therapy to reduce the risk of future UTIs if there is no contraindication to vaginal estrogen therapy.”1

The urology guideline for recurrent UTIs, 2025

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From $39/month, billed yearly

“Isn’t estrogen risky?”

This is a low dose that works where you put it, and very little reaches your bloodstream.

In November 2025 the FDA moved to take the old boxed warning off these products.2

If you’ve had breast cancer, ask your oncologist first.

Two hands holding a tube of estradiol vaginal cream

How it works

  1. Choose your plan

    The cream, the tablet or both.

  2. Do your online visit

    About five minutes, from home. A licensed doctor reviews it.

  3. Get it in the mail

    Free, in a plain box. Then text your doctor anytime.

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From $39/month, billed yearly

From Antha patients

  • “Where I live, it’s hard to find anyone who specializes in menopause care. Antha made it easy to get the help I needed without the hunt. So glad I found them!”
    Monica R.
  • “Busy working mom, no time for doctor visits. I ordered from the coffee line in minutes… I pee less and everything just works better down there!”
    Kate C.
  • “I will never stop using vaginal estrogen! No more sandpaper sex for me!”
    Stephanie M.

Choose your treatment

How you pay
  • A tube of estradiol vaginal cream
    Often best for UTIs

    The Cream

    Reaches the urethra, where a tablet may not.

    $39/mo$468 billed yearly

    Get the Cream
  • A tube of estradiol vaginal cream beside a pack of tablet applicators
    Best value

    The Combo

    Cream and tablets, for less than buying both.

    $69/mo$828 billed yearly

    Get the Combo
  • A pack of estradiol tablets in pre-filled applicators

    The Tablet

    Pre-filled applicators. May not reach the urethra.

    $59/mo$708 billed yearly

    Get the Tablet

Every plan includes

  • Online visit with a licensed doctor
  • Automatic refills for a year
  • Text your doctor anytime
  • Free, discreet shipping
  • FSA and HSA cards work

Antha doesn’t bill Medicare or insurance, so the price you see is the whole price.

Verify Approval for www.antha.health

Antha is LegitScript certified. Your information is private and HIPAA-protected.

Founded and run by women

“We founded Antha to help women understand their options for managing vaginal health across all life stages and hormonal changes, and to make local vaginal hormone therapy more accessible when they need it.”
Dr. Natalie Barnett, PhD Founder and CEO of Antha

Questions

Will this treat a UTI I have right now?

No. Vaginal estrogen helps prevent the next UTI. It doesn’t clear an infection you already have. If you have symptoms now, call your doctor or go to urgent care today. Fever, back pain or blood in your urine need care right away.

Will Medicare or my insurance pay for this?

No. Antha doesn’t bill Medicare or insurance. The price you see is the whole price, and FSA and HSA cards work.

I take cranberry or D-mannose. Should I stop?

You don’t have to. Those work on bacteria, and vaginal estrogen works on the tissue, so they can be used together.

Will anyone know what’s in the box?

No. Every order ships free in plain, unbranded packaging.

Something else on your mind? Email support@antha.health.

Treat the cause, not just the infection.

Prescribed online by licensed doctors. Shipped free.

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From $39/month, billed yearly

Important safety information

Estradiol vaginal cream and estradiol vaginal inserts (the tablets) are prescription estrogen medicines. They are FDA-approved to treat menopause-related changes of the vulva and vagina. Using vaginal estrogen to lower the risk of recurrent UTIs follows the AUA/CUA/SUFU guideline; your doctor will decide whether it is right for you. Vaginal estrogen does not treat an active urinary tract infection.

Labels are being updated. In November 2025 the FDA asked makers of vaginal estrogen to remove the boxed warning about cardiovascular disease, breast cancer, probable dementia and endometrial cancer, and to focus the safety information on the local vaginal form.2 Until a product’s label is updated it may still carry the older warning, so read the label that comes with your medicine.

Do not use estrogen if you have unusual vaginal bleeding, are allergic to estradiol, or are pregnant. Tell your doctor about any vaginal bleeding right away.

Common side effects include headache, breast pain, vaginal spotting or discharge, and stomach cramps or bloating. This is not all the information about these medicines. Read the full Prescribing Information on DailyMed and talk with your doctor.

  1. Recurrent Uncomplicated Urinary Tract Infections in Women: AUA/CUA/SUFU Guideline. 2019, amended 2025.
  2. HHS Advances Women’s Health, Removes Misleading FDA Warnings on Hormone Replacement Therapy. US Food and Drug Administration, November 10, 2025.
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